Citalopram hydrobromide takes place as a great white to beige powder. Citalopram hydrobromide is sparingly dissolvable in water and also dissolvable in ethanol.
Citalopram hydrobromide 10 milligrams capsules have an ivory body as well as yellow cap and also include citalopram hydrobromide equivalent to 10 milligrams citalopram base. Citalopram hydrobromide 20 mg pills have an ivory body and pink cap and also include citalopram hydrobromide comparable to 20 mg citalopram base. Citalopram hydrobromide 40 milligrams pills have an ivory body and also a green cap as well as contain citalopram hydrobromide equivalent to 40 mg citalopram base. The pills also include the complying with non-active elements: corn starch, crospovidone, edible inks, jelly, lactose monohydrate, magnesium stearate, titanium dioxide, and yellow iron oxide. The belowing coloring representatives are made use of in the yellow (10 mg) capsules: D&C Red No. 28, D&C Yellow No. 10, as well as FD&C Yellow No. 6. The adhering to colouring representatives are used in the pink (20 mg) pills: D&C Red No. 28, D&C Yellow No. 10, FD&C Blue No. 1, as well as FD&C Red No. 40. The adhering to coloring agents are utilized in the green (40 milligrams) pills: D&C Yellow No. 10 as well as FD&C Blue No.
The mechanism of activity of citalopram hydrobromide as an antidepressant is presumed to be connecteded to potentiation of serotonergic tactics in the main anxious system (CNS) arising from its restraint of CNS neuronal reuptake of serotonin (5-HT). Artificial insemination as well as in vivo research studies in pets recommend that citalopram is a highly selective serotonin reuptake inhibitor (SSRI) with very little effects on norepinephrine (NE) and dopamine (DA) neuronal reuptake. Resistance to the restraint of 5-HT uptake is not generated by lasting (14 day) treatment of rats with citalopram. Citalopram is a racemic mix (50/50), as well as the restraint of 5-HT reuptake by citalopram is mainly as a result of the (S)-enantiomer.